The HMGB1 ELISA Kit was developed by Shino-Test Corporation, Japan, in cooperation with Prof. Dr. Ikuro Maruyama, Kagoshima University. The product is exclusively distributed worldwide by IBL International except in Japan, China (incl. Hong Kong) and Taiwan.
About HMGB1:
HMGB1 is an ubiquitous protein that can be found in all animals in the cytosol and the nucleus of the cells.
As a nucleus-binding protein it regulates amongst other things the gene transcription.
HMGB1 plays a major role in the pathogenesis of a lot of diseases.
So HMGB1 is important in the development and survival of tumours. It regulates by interaction with RAGE autophagy. It is late mediator in sepsis. It organizes cross-talk of NKs and DCs in viral infections. These findings represent only a small overview of HMGB1's role in medical research.
About HMGB1:
HMGB1 is an ubiquitous protein that can be found in all animals in the cytosol and the nucleus of the cells.
As a nucleus-binding protein it regulates amongst other things the gene transcription.
HMGB1 plays a major role in the pathogenesis of a lot of diseases.
So HMGB1 is important in the development and survival of tumours. It regulates by interaction with RAGE autophagy. It is late mediator in sepsis. It organizes cross-talk of NKs and DCs in viral infections. These findings represent only a small overview of HMGB1's role in medical research.
| Katalognummer | ST51011 |
| Kits-Größe | 12 x 8 |
| Methode / Technologie | ELISA |
| Inkubationszeit | 1 x 18h, 1 x 2h, 1 x 30min. |
| Standardbereich | 2.5 - 80 ng/mL (HS: 0.313 - 10 ng/mL) |
| Probenarten / -volumina | 10 µl serum, plasma, cell culture supernatant et.al |
| Substrat / Isotop | TMB 450 nm |