17-OH-progesterone (17-OHP) is the most suitable biochemical marker for the diagnosis of Congenital Adrenal Hyperplasia (CAH). CAH has a prevalence of around 1-20 in 10,000 children and is one of the most frequent inborn endocrine disorders.
The spectrum of clinical presentations ranges from forms with neonatal symptoms, i.e. salt wasting and simple virilizing forms, to non-classical forms that might not manifest until adulthood.
Measuring this steroid enables early diagnosis and treatment in patients suffering from CAH.
17-OHP is secreted in abundant excess in affected infants due to 21-hydroxylase deficiency.
Female patients with late-onset CAH usually have 17-OHP concentrations above the reference interval for the follicular phase of the menstrual cycle.
The IBL International 17-OH-Progesterone ELISA shows following advantages:
• Excellent analytical characteristics
• Age dependant reference ranges for children
• Serum, plasma ELISA: EU: CE, US: IVD
• Easy to adapt to automated instruments
The spectrum of clinical presentations ranges from forms with neonatal symptoms, i.e. salt wasting and simple virilizing forms, to non-classical forms that might not manifest until adulthood.
Measuring this steroid enables early diagnosis and treatment in patients suffering from CAH.
17-OHP is secreted in abundant excess in affected infants due to 21-hydroxylase deficiency.
Female patients with late-onset CAH usually have 17-OHP concentrations above the reference interval for the follicular phase of the menstrual cycle.
The IBL International 17-OH-Progesterone ELISA shows following advantages:
• Excellent analytical characteristics
• Age dependant reference ranges for children
• Serum, plasma ELISA: EU: CE, US: IVD
• Easy to adapt to automated instruments
| Katalognummer | RE52071 |
| Kits-Größe | 12 x 8 |
| Methode / Technologie | ELISA |
| Inkubationszeit | 1 x 60 min, 1 x 30 min |
| Standardbereich | 0.15 - 20 ng/mL |
| Probenarten / -volumina | 25 µL serum, plasma |
| Substrat / Isotop | TMB 450 nm |