Immunoassays for Amyloids & Others

The understanding of the mechanisms underlying neurological disease is increasingly growing by the increased insight of how protein interaction can lead to the formation of unique complexes. One of the hallmarks of Alzheimer's disease is the accumulation of amyloid plaques between nerve cells (neurons) in the brain. Amyloid-beta is a protein fragment that is snipped from an amyloid precursor protein (APP). In a healthy brain these protein fragments are broken down and eliminated. In Alzheimer's disease the fragments accumulate to form hard, insoluble plaques. Creutzfeldt-Jakob disease (CJD) occurs when prion protein start folding into abnormal three dimensional shapes which replicate by converting their properly folded counterparts and form aggregates. A neurological disease with partial Alzheimer's disease-like symptoms is idiopathic normal pressure hydrocephalus (iNPH), which can be differentially diagnosed by measuring leucine-rich alpha-2-glycoprotein (LRG). IBL International offers the most comprehensive product portfolio around the APP-cascade.

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Method / Technology:
  1. non-radioactive (2)

Regulatory Status:
  1. RUO (2)

2 Item(s)

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    Catalog No. Product Name List Price Quantity
  1. New Product
    RE59631

     hTau total ELISA

    hTau total ELISA ...more
    List Price $921
    Kit size Method Incubation time Standard range Specimen / Volumes Substrate / isotope
    12 x 8 ELISA 1 x 2h, 1 x 90min, 1 x 30min 25 - 1000 pg/mL 25µL CSF TMB 450nm
  2. Highlight
    30112458

     NF-light® (Neurofilament-light) RUO ELISA

    The NF-Light® (Neurofilament light) ELISA allows fast (3 hours) quantification of the neurofilament light chain. The assessment requires as little as 50 µL of CSF. Neurofilament light is found to b ...more

    List Price $1,014
    Kit size Method Incubation time Standard range Specimen / Volumes Substrate / isotope
    12 x 8 ELISA 1 x 1h, 1 x 45min, 1 x 30min, 1 x 15min 100 - 10000 ng/L 50 µL CSF TMB 450nm

2 Item(s)

per page