Family: Brucellaceae
Genus: Brucella
Brucellosis is an infectious disease caused by small ellipsoid, gram-negative bacteria. Brucellosis is a zoonosis. Patients get infected by contact with infected animals or by swallowing meat or unpasteurized milk from infected animals. Infected humans are not contagious.
There are six different subtypes: B. abortus, B. melitensis, B. suis, B. canis, B. ovis and B. neotomae. The incubation period may take one to three weeks, for B. melitensis up to 3 months. B. abortus causes the Bang’s Disease. Typical symptoms for Bang’s Disease are periodically occuring fever, splenomegaly and swelling of lymph nodes. In some cases an inflammation of different joints and organs occurs. B. melitensis causes the Malta Fever. Infection with B. melitensis almost always leads to a manifest illness.
Serological methods like agglutination, complement fixation reaction, Brucella Coombs test and ELISA are good alternatives. 85% of the Brucellosis cases are diagnosed with serological methods. Antibodies against IgG as well as IgM should always be tested. During the first days, IgM is the only immunoglobulin appearing. As the disease progresses, IgM recedes quantitatively and IgG becomes predominant. In chronic brucellosis IgG may be produced for extended periods.
IBL International offers ELISA kits for the immunglobulin subclasses IgG, IgA and IgM.
In case of questions regarding the products do not hesitate to contact us.
Genus: Brucella
Brucellosis is an infectious disease caused by small ellipsoid, gram-negative bacteria. Brucellosis is a zoonosis. Patients get infected by contact with infected animals or by swallowing meat or unpasteurized milk from infected animals. Infected humans are not contagious.
There are six different subtypes: B. abortus, B. melitensis, B. suis, B. canis, B. ovis and B. neotomae. The incubation period may take one to three weeks, for B. melitensis up to 3 months. B. abortus causes the Bang’s Disease. Typical symptoms for Bang’s Disease are periodically occuring fever, splenomegaly and swelling of lymph nodes. In some cases an inflammation of different joints and organs occurs. B. melitensis causes the Malta Fever. Infection with B. melitensis almost always leads to a manifest illness.
Serological methods like agglutination, complement fixation reaction, Brucella Coombs test and ELISA are good alternatives. 85% of the Brucellosis cases are diagnosed with serological methods. Antibodies against IgG as well as IgM should always be tested. During the first days, IgM is the only immunoglobulin appearing. As the disease progresses, IgM recedes quantitatively and IgG becomes predominant. In chronic brucellosis IgG may be produced for extended periods.
IBL International offers ELISA kits for the immunglobulin subclasses IgG, IgA and IgM.
In case of questions regarding the products do not hesitate to contact us.
| Catalog number | RE56831 |
| Kit size | 12 x 8 |
| Method / Technology | ELISA |
| Incubation time | 1 x 1 h, 1 x 30 min, 1 x 20 min |
| Standard range | 0 - 200 U/mL, cut-off 10 U/mL |
| Specimen / Volumes | 5 µL serum, plasma |
| Substrate / isotope | TMB 450 nm |