NF-light® (Neurofilament-light) RUO ELISA

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Details for:  NF-light® (Neurofilament-light) RUO ELISA

The NF-Light® (Neurofilament light) ELISA allows fast (3 hours) quantification of the neurofilament light chain. The assessment requires as little as 50 µL of CSF. Neurofilament light is found to be elevated in neurodegenerative disorders that are associated with the destruction of white matter (substantia alba).

The assay was developed by UmanDiagnostics, a company focusing on the development of immunochemical tools for research of neurological and traumatic injuries. The NF-Light® (Neurofilament light) ELISA is exclusively distributed by IBL International.

Neurofilaments are the backbone of the neuronal cytoskeleton. Inside the axons, phosphorylation and dephosphorylation of the neurofilaments regulate, respectively, the expansion and contraction of the microtubules. The neurofilament light (NF-light) chain is the stoichiometrically most common form compared to other isoforms, such as medium and heavy chains. It is rapidly released after axonal destruction and remains highly stable (at least for 8 days, even at room temperature).

For concrete data please consult the Instruction for Use in the download box on the right side.

Catalog No. 30112458

NF-light® (Neurofilament-light) RUO ELISA
List Price $1,054
Kit size 12 x 8
Method ELISA
Incubation time 1 x 1h, 1 x 45min, 1 x 30min, 1 x 15min
Standard range 100 - 10000 ng/L
Specimen / Volumes 50 µL CSF
Substrate / isotope TMB 450nm
Regulatory Status: For research use only