CD134 (OX40) ELISA

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Details for:  CD134 (OX40) ELISA
OX40 (CD134) is a member of the tumor necrosis (TNF) receptor superfamily and known to be an important costimulatory molecule expressed on activated T-cells. Interaction of OX40 with its ligand, OX40L, is thought to be important in T cell activation through T cell/antigen-presenting cell (APC) interaction. Ligation of OX40 induces clonal expansion and survival of CD4 cells during primary responses, and results in the accumulation of greater numbers of memory cells with time. A soluble isoform of OX40 has been described. Measurement of this molecule may have diagnostic value in polymyositis and granulomatous myopathy, in T cell lymphoma and lymphomatoid papulosis, in proliferative lupus nephritis, in rheumatoid arthritis, in HIV infection, in viral infections of the lung, in the regulation of graft-versus-host disease, in myocarditis and dilated cardiomyopathy.

Synonyms: OX 40L receptor, ACT 35
For concrete data please consult the Instruction for Use in the download box on the right side.

Catalog No. BE59401

CD134 (OX40) ELISA
List Price $501
Kit size 12 x 8
Method ELISA
Incubation time 1 x 2h, 1 x 1h, 1 x 10min.
Standard range 78 - 5000 pg/mL
Specimen / Volumes 25µL serum, plasma, cell culture supernatant et al.
Substrate / isotope TMB 450 nm
Regulatory Status: For research use only