CD23 ELISA

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Details for:  CD23 ELISA
Formerly sold as BE59051.

CD23 is described as a 45 kDa protein found on the surface of IgM bearing B cells, eosinophils, macrophages and some T and NK cells. It is also found on EBV-transformed B cells. Additionally, a released form has been described. When first released the CD23 molecule is 35 kDa; however, this form is quickly cleaved to obtain the more stable, soluble form which is 25 kDa in size. Recently the structure of the CD23 molecule was characterized by cloning and sequencing techniques. Soluble CD23 has been shown to be the B cell growth factor (BCGF). Soluble CD23 is also referred to as Blast-2 and as the low affinity IgE receptor (FCeRII). It has been speculated that CD23 may up-regulate IgE synthesis in conjunction with T cell promoted interleukin-4; however, the specific physiologic role of this molecule is not yet well understood.

Synonyms: Immunoglobulin E receptor low affinity II
For concrete data please consult the Instruction for Use in the download box on the right side.

Catalog No. 30150479

CD23 ELISA
List Price $501
Kit size 12 x 8
Method ELISA
Incubation time 1 x 2 h, 1 x 1 h, 1 x 10 min
Standard range 12.5 - 400 U/mL
Specimen / Volumes 100 µL serum, plasma, cell culture supernatant et al.
Substrate / isotope TMB 450 nm
Regulatory Status: For research use only

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