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Details for:  CD30 ELISA
Formerly sold as BE59151.

Characterization of the CD30 antigen has shown it to be in its mature form a transmembrane protein of about 120kDa elaborated from an 84kD cytoplasmic precursor primarily through glycosylation. Interactions of the cytokine receptor CD30 with its ligand induces pleiotropic biologic effects, such as differentiation, activation, proliferation and cell death. CD30 furthermore seems to be involved in the control of the CD40/CD40L signal, T-cell proliferation and B-cell maturation induced by T-cell cytokines. Thus, CD30 seems to transmit information that is essential for the immune response. An 85kDa soluble form of the CD30 molecule (sCD30) has been shown to be released by CD30+ cell in vitro and in vivo. It is probably derived from the 120kDa membrane bound molecule by proteolytic cleavage. Serum sCD30 detection can be regarded as a marker of the amount of CD30+ cells present in the body.

Synonyms: Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Lymphocyte activation antigen CD30, KI-1 antigen, CD antigen CD30
For concrete data please consult the Instruction for Use in the download box on the right side.

Catalog No. 30150498

List Price $501
Kit size 12 x 8
Method ELISA
Incubation time 1 x 3 h, 1 x 10 min
Standard range 1.6 - 100 U/mL
Specimen / Volumes 25 µL serum, plasma, urine, cell culture supernatant
Substrate / isotope TMB 450 nm
Regulatory Status: For research use only