CD44var (v6) ELISA

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Details for:  CD44var (v6) ELISA
Alternative splicing of the mRNA gives rise to the different isoforms, containing inserts of varying sizes in the extracellular domain of the molecule (exons v2-v10). All CD44 isoforms are variably glycosylated. In contrast to standard CD44 (CD44std) which is almost ubiquitously expressed, the variety of CD44 isoforms (CD44var) have a much more restricted distribution, e.g., on activated lymphocytes and macrophages (exon v6).
The sCD44var(v6) ELISA detects all circulating CD44 isoforms comprising the sCD44var(v6) sequences.
Determination of sCD44var(v6) will provide more detailed insight into different pathological modifications during cancer and other diseases.

Synonyms: VFF-7 Phagocytic glycoprotein I, Hermes antigen
For concrete data please consult the Instruction for Use in the download box on the right side.

Catalog No. BE59251

CD44var (v6) ELISA
List Price $501
Kit size 12 x 8
Method ELISA
Incubation time 1 x 3 h, 1 x 10 min
Standard range 0.32 - 10 ng/mL
Specimen / Volumes 10 µL serum, plasma, urine, cell culture supernatant et al.
Substrate / isotope TMB 450 nm
Regulatory Status: For research use only